Sequence Detail

ID/Version

Q8CIP4 Q80T81 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=MAP/microtubule affinity-regulating kinase 4 {ECO:0000305}; EC=2.7.11.1 {ECO:0000250|UniProtKB:Q96L34};

Provider

SWISS-PROT

Sequence

Polypeptide 752 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mark4	MAP/microtubule affinity regulating kinase 4	85	96	4	9

Sequence references in MGI

J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:192469 Sun C, et al., Inactivation of MARK4, an AMP-activated protein kinase (AMPK)-related kinase, leads to insulin hypersensitivity and resistance to diet-induced obesity. J Biol Chem. 2012 Nov 2;287(45):38305-15
J:249560 Li X, et al., MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism. Nat Commun. 2017 Jun 28;8:15986
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89