Sequence Detail

ID/Version

Q8CIF6 Q922R2 Q80XD7 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=SID1 transmembrane family member 2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 832 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sidt2	SID1 transmembrane family, member 2	26	101	3	11

Sequence references in MGI

J:167079 Jialin G, et al., SID1 transmembrane family, member 2 (Sidt2): a novel lysosomal membrane protein. Biochem Biophys Res Commun. 2010 Nov 26;402(4):588-94
J:204228 Gao J, et al., Impaired glucose tolerance in a mouse model of sidt2 deficiency. PLoS One. 2013;8(6):e66139
J:224606 Li W, et al., Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1. J Biol Chem. 2015 Jul 31;290(31):18904-13
J:236042 Gao J, et al., Spontaneous nonalcoholic fatty liver disease and ER stress in Sidt2 deficiency mice. Biochem Biophys Res Commun. 2016 Aug 5;476(4):326-32
J:243409 Contu VR, et al., Lysosomal targeting of SIDT2 via multiple YxxPhi motifs is required for SIDT2 function in the process of RNautophagy. J Cell Sci. 2017 Sep 01;130(17):2843-2853
J:243459 Aizawa S, et al., Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12(3):565-78
J:243615 Takahashi M, et al., SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells. RNA Biol. 2017 Mar 09;:1-10
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89