Sequence Detail

ID/Version

Q8CI75 Q8BMG9 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=DIS3-like exonuclease 2 {ECO:0000255|HAMAP-Rule:MF_03045}; EC=3.1.13.- {ECO:0000255|HAMAP-Rule:MF_03045};

Provider

SWISS-PROT

Sequence

Polypeptide 870 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dis3l2	DIS3 like 3'-5' exoribonuclease 2	61	99	3	28

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:197683 Chang HM, et al., A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature. 2013 May 9;497(7448):244-8
J:214591 Faehnle CR, et al., Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. Nature. 2014 Oct 9;514(7521):252-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89