Sequence Detail

ID/Version

Q8CHQ0 E9QPM9 Q99JG8 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=F-box only protein 4 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 385 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fbxo4	F-box protein 4	62	98	3	6

Sequence references in MGI

J:162977 Barbash O, et al., Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation. Oncogene. 2009 Dec 10;28(49):4317-25
J:183656 Kanie T, et al., Genetic reevaluation of the role of F-box proteins in cyclin D1 degradation. Mol Cell Biol. 2012 Feb;32(3):590-605
J:255973 Qie S, et al., Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma. Nat Commun. 2017 Nov 16;8(1):1534
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89