Sequence Detail

ID/Version

Q8CHG5 Q8C5W5 Q80YC4 Q6P9Q1 (UniProt | EBI)

Last sequence update: 2005-03-29
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1; EC=2.3.2.26 {ECO:0000250|UniProtKB:O15033};AltName: Full=Apoptosis-resistant HECT-type E3 ubiquitin transferase 1;

Provider

SWISS-PROT

Sequence

Polypeptide 823 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Arel1	apoptosis resistant E3 ubiquitin protein ligase 1	27	96	3	10

Sequence references in MGI

J:86755 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2002 Oct 31;9(5):179-88
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:198601 Kim JB, et al., Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS. J Biol Chem. 2013 Apr 26;288(17):12014-21
J:280563 Lear TB, et al., KIAA0317 regulates pulmonary inflammation through SOCS2 degradation. JCI Insight. 2019 Oct 3;4(19)