About   Help   FAQ
Sequence Detail
Q8CGB3 Q7TN77 Q69ZG3 Q8BJC8 (UniProt | EBI) Last sequence update: 2006-04-04
Last annotation update: 2015-09-16
from provider
RecName: Full=Uveal autoantigen with coiled-coil domains and ankyrin repeats;AltName: Full=Nuclear membrane-binding protein; Short=Nucling;
Polypeptide 1411 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats 25 3 9 15
Sequence references in MGI J:84854 Sakai T, et al., Identification of a novel, embryonal carcinoma cell-associated molecule, Nucling, that is pp-regulated during cardiac muscle differentiation. J Biochem. 2003 Apr;133(4):429-36
J:89918 Liu L, et al., Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling. Biochem J. 2004 May 15;380(Pt 1):31-41
J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:93333 Sakai T, et al., Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis. J Biol Chem. 2004 Oct 24;279(39):41131-40
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:222141 Mori Y, et al., Small GTPase Rab39A interacts with UACA and regulates the retinoic acid-induced neurite morphology of Neuro2A cells. Biochem Biophys Res Commun. 2013 May 24;435(1):113-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.0
The Jackson Laboratory