Sequence Detail

ID/Version

Q8CG71 Q8C673 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Prolyl 3-hydroxylase 2 {ECO:0000312|MGI:MGI:2146663}; EC=1.14.11.7 {ECO:0000305|PubMed:25645914};AltName: Full=Leprecan-like protein 1 {ECO:0000303|PubMed:15063763};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 703 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	P3h2	prolyl 3-hydroxylase 2	28	105	3	8

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:138660 Tiainen P, et al., Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV. J Biol Chem. 2008 Jul 11;283(28):19432-9
J:206377 Pokidysheva E, et al., Biological role of prolyl 3-hydroxylation in type IV collagen. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):161-6
J:220554 Hudson DM, et al., Post-translationally Abnormal Collagens of Prolyl 3-Hydroxylase-2 Null Mice Offer a Pathobiological Mechanism for the High Myopia Linked to Human LEPREL1 Mutations. J Biol Chem. 2015 Mar 27;290(13):8613-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89