Sequence Detail

ID/Version

Q8CFT2 Q8CGD1 Q80TK9 Q8CFQ8 (UniProt | EBI)

Last sequence update: 2008-02-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Histone-lysine N-methyltransferase SETD1B; EC=2.1.1.364 {ECO:0000250|UniProtKB:Q9UPS6};AltName: Full=SET domain-containing protein 1B;

Provider

SWISS-PROT

Sequence

Polypeptide 1985 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Setd1b	SET domain containing 1B	39	106	3	24

Sequence references in MGI

J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:208420 Bledau AS, et al., The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation. Development. 2014 Mar;141(5):1022-35
J:264156 Schmidt K, et al., The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice. Elife. 2018 Jun 19;7:e27157
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89