About   Help   FAQ
Sequence Detail
ID/Version
Q8CFN5 Q8R0H1 Q9QW20 Q9D7L0 (UniProt | EBI) Last sequence update: 2005-01-04
Last annotation update: 2014-03-19
Sequence
description
from provider
RecName: Full=Myocyte-specific enhancer factor 2C;
Provider SWISS-PROT
Sequence
Polypeptide 474 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Mef2c myocyte enhancer factor 2C 152 33 5 6
Sequence references in MGI J:17643 Martin JF, et al., Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5282-6
J:37685 Lin X, et al., The expression of MEF2 genes is implicated in CNS neuronal differentiation. Brain Res Mol Brain Res. 1996 Dec;42(2):307-16
J:40724 Lin Q, et al., Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science. 1997 May 30;276(5317):1404-7
J:50309 Lin Q, et al., Requirement of the MADS-box transcription factor MEF2C for vascular development. Development. 1998 Nov;125(22):4565-74
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:111229 Creemers EE, et al., Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR. Mol Cell. 2006 Jul 7;23(1):83-96
J:136292 Wilker PR, et al., Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation. Nat Immunol. 2008 Jun;9(6):603-12
J:138188 Barbosa AC, et al., MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9391-6
J:138189 Li H, et al., Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9397-402
J:148288 Gekas C, et al., Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. Blood. 2009 Apr 9;113(15):3461-71
J:159054 Liu GH, et al., Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells. PLoS One. 2009;4(9):e7031
J:172163 Angelelli C, et al., Differentiation-dependent lysine 4 acetylation enhances MEF2C binding to DNA in skeletal muscle cells. Nucleic Acids Res. 2008 Feb;36(3):915-28

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory