ID/Version |
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Sequence description from provider |
RecName: Full=Myocyte-specific enhancer factor 2C {ECO:0000305};AltName: Full=Myocyte enhancer factor 2C {ECO:0000312|MGI:MGI:99458}; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
474
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
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Sequence references in MGI |
J:17643
Martin JF, et al., Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5282-6
J:37685 Lin X, et al., The expression of MEF2 genes is implicated in CNS neuronal differentiation. Brain Res Mol Brain Res. 1996 Dec;42(2):307-16 J:40724 Lin Q, et al., Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science. 1997 May 30;276(5317):1404-7 J:50309 Lin Q, et al., Requirement of the MADS-box transcription factor MEF2C for vascular development. Development. 1998 Nov;125(22):4565-74 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:111229 Creemers EE, et al., Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR. Mol Cell. 2006 Jul 7;23(1):83-96 J:136292 Wilker PR, et al., Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation. Nat Immunol. 2008 Jun;9(6):603-12 J:138188 Barbosa AC, et al., MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9391-6 J:138189 Li H, et al., Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9397-402 J:148288 Gekas C, et al., Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. Blood. 2009 Apr 9;113(15):3461-71 J:159054 Liu GH, et al., Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells. PLoS One. 2009;4(9):e7031 J:172163 Angelelli C, et al., Differentiation-dependent lysine 4 acetylation enhances MEF2C binding to DNA in skeletal muscle cells. Nucleic Acids Res. 2008 Feb;36(3):915-28 J:175110 Hosking BM, et al., SOX18 directly interacts with MEF2C in endothelial cells. Biochem Biophys Res Commun. 2001 Sep 21;287(2):493-500 J:181087 Mayers CM, et al., The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice. J Biol Chem. 2010 Apr 16;285(16):12344-54 J:283181 Guo A, et al., E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator. Science. 2018 Dec 21;362(6421) J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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