Sequence Detail

ID/Version

Q8CFI0 Q8BRT9 Q8BS42 Q99PK2 (UniProt | EBI)

Last sequence update: 2005-08-30
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase NEDD4-like; EC=2.3.2.26 {ECO:0000250|UniProtKB:P46934}; EC=2.3.2.36 {ECO:0000250|UniProtKB:P46934};AltName: Full=HECT-type E3 ubiquitin transferase NED4L;AltName: Full=NEDD4.2;AltName: Full=Nedd4-2

Provider

SWISS-PROT

Sequence

Polypeptide 1004 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	86	104	3	43

Sequence references in MGI

J:66806 Kamynina E, et al., A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel. FASEB J. 2001 Jan;15(1):204-214
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:333673 Fotia AB, et al., Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2. J Biol Chem. 2004 Jul 9;279(28):28930-5