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Sequence Detail
ID/Version
Q8CFH6 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Serine/threonine-protein kinase SIK2; EC=2.7.11.1 {ECO:0000269|PubMed:12624099, ECO:0000269|PubMed:29211348};AltName: Full=Salt-inducible kinase 2; Short=SIK-2;AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 2;
Provider SWISS-PROT
Sequence
Polypeptide 931 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Sik2 salt inducible kinase 2 30 98 4 28
Sequence references in MGI J:83587 Horike N, et al., Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2. J Biol Chem. 2003 May 16;278(20):18440-7
J:121527 Katoh Y, et al., Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade. FEBS J. 2006 Jun;273(12):2730-48
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:313576 Nefla M, et al., Salt inducible kinases 2 and 3 are required for thymic T cell development. Sci Rep. 2021 Nov 3;11(1):21550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory