Sequence Detail

ID/Version

Q8CFH6 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase SIK2; EC=2.7.11.1 {ECO:0000269|PubMed:12624099, ECO:0000269|PubMed:29211348};AltName: Full=Salt-inducible kinase 2; Short=SIK-2;AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 2;

Provider

SWISS-PROT

Sequence

Polypeptide 931 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sik2	salt inducible kinase 2	47	98	4	28

Sequence references in MGI

J:83587 Horike N, et al., Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2. J Biol Chem. 2003 May 16;278(20):18440-7
J:121527 Katoh Y, et al., Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade. FEBS J. 2006 Jun;273(12):2730-48
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:313576 Nefla M, et al., Salt inducible kinases 2 and 3 are required for thymic T cell development. Sci Rep. 2021 Nov 3;11(1):21550