Sequence Detail

ID/Version

Q8CF90 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Transcription factor MafA;AltName: Full=Pancreatic beta-cell-specific transcriptional activator;AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog A;

Provider

SWISS-PROT

Sequence

Polypeptide 359 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mafa	MAF bZIP transcription factor A	22	117	3	19

Sequence references in MGI

J:80902 Kataoka K, et al., MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene. J Biol Chem. 2002 Dec 20;277(51):49903-10
J:85091 Matsuoka TA, et al., Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells. Mol Cell Biol. 2003 Sep;23(17):6049-62
J:86942 Kajihara M, et al., Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter. Biochem Biophys Res Commun. 2003 Dec 19;312(3):831-42
J:99126 Zhang C, et al., MafA is a key regulator of glucose-stimulated insulin secretion. Mol Cell Biol. 2005 Jun;25(12):4969-76