Sequence Detail

ID/Version

Q8CBW3 Q3U8V0 Q923I9 Q60747 Q99KH4 Q91ZM5 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Abl interactor 1;AltName: Full=Abelson interactor 1; Short=Abi-1;AltName: Full=Ablphilin-1;AltName: Full=Eps8 SH3 domain-binding protein; Short=Eps8-binding protein;AltName: Full=Spectrin SH3 domain-binding protein 1;AltName:

Provider

SWISS-PROT

Sequence

Polypeptide 481 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Abi1	abl interactor 1	37	103	4	81

Sequence references in MGI

J:29673 Shi Y, et al., Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity. Genes Dev. 1995 Nov 1;9(21):2583-97
J:72871 Courtney KD, et al., Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system. Mol Cell Neurosci. 2000 Sep;16(3):244-57
J:83872 Tani K, et al., Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase. J Biol Chem. 2003 Jun 13;278(24):21685-92
J:88449 Steffen A, et al., Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. EMBO J. 2004 Feb 25;23(4):749-59
J:91021 Echarri A, et al., Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels. Mol Cell Biol. 2004 Jun;24(11):4979-93
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116237 Scita G, et al., EPS8 and E3B1 transduce signals from Ras to Rac. Nature. 1999 Sep 16;401(6750):290-3
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:196111 Disanza A, et al., Eps8 controls actin-based motility by capping the barbed ends of actin filaments. Nat Cell Biol. 2004 Dec;6(12):1180-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89