Sequence Detail

ID/Version

Q8C878 Q9D6B7 O88598 Q3TG68 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=NEDD8-activating enzyme E1 catalytic subunit; EC=6.2.1.64 {ECO:0000250|UniProtKB:Q8TBC4};AltName: Full=NEDD8-activating enzyme E1C;AltName: Full=Ubiquitin-activating enzyme E1C;AltName: Full=Ubiquitin-like modifier-activating enzyme

Provider

SWISS-PROT

Sequence

Polypeptide 462 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Uba3	ubiquitin-like modifier activating enzyme 3	36	98	3	37

Sequence references in MGI

J:54622 Gong L, et al., Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway. J Biol Chem. 1999 Apr 23;274(17):12036-42
J:72808 Tateishi K, et al., The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. J Cell Biol. 2001 Nov 12;155(4):571-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166065 Flomerfelt FA, et al., Tbata modulates thymic stromal cell proliferation and thymus function. J Exp Med. 2010 Oct 25;207(11):2521-32
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89