Sequence Detail

ID/Version

Q8C5S7 Q9JK52 Q3UIN9 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Meiotic recombination protein REC8 homolog;AltName: Full=Cohesin Rec8p;

Provider

SWISS-PROT

Sequence

Polypeptide 591 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rec8	REC8 meiotic recombination protein	40	109	3	10

Sequence references in MGI

J:84400 Lee J, et al., Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis. J Cell Sci. 2003 Jul 1;116(Pt 13):2781-90
J:94208 Bannister LA, et al., Positional cloning and characterization of mouse mei8, a disrupted allele of the meiotic cohesin Rec8. Genesis. 2004 Oct 27;40(3):184-194
J:99402 Xu H, et al., Absence of mouse REC8 cohesin promotes synapsis of sister chromatids in meiosis. Dev Cell. 2005 Jun;8(6):949-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:183411 Fukuda T, et al., Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis. PLoS Genet. 2012 Feb;8(2):e1002485
J:277855 Parvanov ED, et al., PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis. Mol Biol Cell. 2017 Feb 1;28(3):488-499
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89