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Sequence Detail
Q8C503 Q9WUU5 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2021-09-29
from provider
RecName: Full=Signaling threshold-regulating transmembrane adapter 1;AltName: Full=SHP2-interacting transmembrane adapter protein;AltName: Full=Suppression-inducing transmembrane adapter 1;
Polypeptide 180 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Sit1 suppression inducing transmembrane adaptor 1 12 85 2 4
Sequence references in MGI J:62650 Marie-Cardine A, et al., SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation. J Exp Med. 1999 Apr 19;189(8):1181-94
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100408 Simeoni L, et al., The transmembrane adapter protein SIT regulates thymic development and peripheral T-cell functions. Mol Cell Biol. 2005 Sep;25(17):7557-68
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory