Sequence Detail

ID/Version

Q8C4Y3 A0A0X1KG62 Q69ZP4 Q99J41 Q9JJA5 (UniProt | EBI)

Last sequence update: 2003-11-14
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Negative elongation factor B; Short=NELF-B;AltName: Full=Cofactor of BRCA1 {ECO:0000303|PubMed:19340312};

Provider

SWISS-PROT

Sequence

Polypeptide 580 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nelfb	negative elongation factor complex member B	16	100	3	12

Sequence references in MGI

J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:148508 Amleh A, et al., Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis. PLoS One. 2009;4(4):e5034
J:211827 Pan H, et al., Negative elongation factor controls energy homeostasis in cardiomyocytes. Cell Rep. 2014 Apr 10;7(1):79-85
J:268012 Williams LH, et al., Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks. Mol Cell. 2015 Apr 16;58(2):311-322
J:283195 Pan H, et al., Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B. PLoS One. 2015;10(5):e0127422
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89