Sequence Detail

ID/Version

Q8C4U3 Q8R1J4 Q505A2 O08861 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Secreted frizzled-related protein 1 {ECO:0000312|MGI:MGI:892014}; Short=sFRP-1 {ECO:0000312|MGI:MGI:892014};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 314 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sfrp1	secreted frizzled-related protein 1	175	148	4	14

Sequence references in MGI

J:39275 Rattner A, et al., A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2859-63
J:49904 Leimeister C, et al., Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mech Dev. 1998 Jul;75(1-2):29-42
J:60429 Jaspard B, et al., Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart morphogenesis. Mech Dev. 2000 Feb;90(2):263-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:147775 Kwon HS, et al., Myocilin is a modulator of Wnt signaling. Mol Cell Biol. 2009 Apr;29(8):2139-54
J:237943 Jia S, et al., Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. Dev Biol. 2016 Dec 01;420(1):110-119