Sequence Detail

ID/Version

Q8C2S0 (UniProt | EBI)

Last sequence update: 2012-11-28
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Ubiquitin carboxyl-terminal hydrolase 44; EC=3.4.19.12 {ECO:0000269|PubMed:23187126, ECO:0000269|PubMed:33937266};AltName: Full=Deubiquitinating enzyme 44;AltName: Full=Ubiquitin thioesterase 44;AltName: Full=Ubiquitin-specific-proce

Provider

SWISS-PROT

Sequence

Polypeptide 711 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Usp44	ubiquitin specific peptidase 44	20	96	3	20

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:190274 Zhang Y, et al., Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia. PLoS One. 2011;6(8):e23389
J:193965 Zhang Y, et al., USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis. J Clin Invest. 2012 Dec 3;122(12):4362-74
J:314115 Zhang Y, et al., USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors. Front Cell Dev Biol. 2021;9:663411