Sequence Detail

ID/Version

Q8C1A3 Q3U2C6 Q8R0Y3 (UniProt | EBI)

Last sequence update: 2011-05-31
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Methionine synthase reductase; Short=MSR; EC=1.16.1.8 {ECO:0000250|UniProtKB:Q9UBK8};AltName: Full=Aquacobalamin reductase; Short=AqCbl reductase;

Provider

SWISS-PROT

Sequence

Polypeptide 696 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mtrr	5-methyltetrahydrofolate-homocysteine methyltransferase reductase	47	105	3	49

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:137550 Deng L, et al., Methionine synthase reductase deficiency results in adverse reproductive outcomes and congenital heart defects in mice. Mol Genet Metab. 2008 Jul;94(3):336-42
J:201187 Padmanabhan N, et al., Mutation in folate metabolism causes epigenetic instability and transgenerational effects on development. Cell. 2013 Sep 26;155(1):81-93
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89