Sequence Detail

ID/Version

Q8BZZ3 Q8BIV9 Q8VDP8 (UniProt | EBI)

Last sequence update: 2003-06-20
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=NEDD4-like E3 ubiquitin-protein ligase WWP1; EC=2.3.2.26 {ECO:0000250|UniProtKB:Q9H0M0};AltName: Full=HECT-type E3 ubiquitin transferase WWP1;AltName: Full=WW domain-containing protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 918 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wwp1	WW domain containing E3 ubiquitin protein ligase 1	31	98	2	50

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:108965 Jones DC, et al., Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science. 2006 May 26;312(5777):1223-7
J:114067 Conkright MD, et al., Lung Kruppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase. J Biol Chem. 2001 Aug 3;276(31):29299-306
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:162979 Li Y, et al., WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer. Oncogene. 2009 Aug 20;28(33):2948-58