Sequence Detail

ID/Version

Q8BZT7 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Group 3 secretory phospholipase A2; EC=3.1.1.4 {ECO:0000250|UniProtKB:Q9NZ20};AltName: Full=Group III secretory phospholipase A2; Short=GIII sPLA2; Short=sPLA2-III;AltName: Full=Phosphatidylcholine 2-acylhydrolase 3;F

Provider

SWISS-PROT

Sequence

Polypeptide 504 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pla2g3	phospholipase A2, group III	92	97	3	2

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:161462 Sato H, et al., Group III secreted phospholipase A2 regulates epididymal sperm maturation and fertility in mice. J Clin Invest. 2010 May 3;120(5):1400-14
J:197334 Taketomi Y, et al., Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis. Nat Immunol. 2013 Jun;14(6):554-63
J:256369 Murase R, et al., Group III phospholipase A2 promotes colitis and colorectal cancer. Sci Rep. 2017 Sep 25;7(1):12261
J:289093 Masuda S, et al., Human group III secreted phospholipase A2 promotes neuronal outgrowth and survival. Biochem J. 2008 Jan 15;409(2):429-38