Sequence Detail

ID/Version

Q8BYJ6 Q149C1 Q8BXM2 Q3T9E8 Q5DU23 Q66JU2 Q8BMH6 Q6P2M2 Q149C0 Q3TAQ5 (UniProt | EBI)

Last sequence update: 2005-06-07
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=TBC1 domain family member 4;AltName: Full=Akt substrate of 160 kDa; Short=AS160;

Provider

SWISS-PROT

Sequence

Polypeptide 1307 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tbc1d4	TBC1 domain family, member 4	16	99	3	13

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:111856 Kramer HF, et al., Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle. Diabetes. 2006 Jul;55(7):2067-76
J:111858 Treebak JT, et al., AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits. Diabetes. 2006 Jul;55(7):2051-8
J:135564 Bouzakri K, et al., Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells. Diabetes. 2008 May;57(5):1195-204
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87