Sequence Detail

ID/Version

Q8BXG3 Q924M2 Q9CUS6 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Intraflagellar transport protein 57 homolog;AltName: Full=HIP1-interacting protein;

Provider

SWISS-PROT

Sequence

Polypeptide 429 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ift57	intraflagellar transport 57	38	98	3	4

Sequence references in MGI

J:65500 Pazour GJ, et al., Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol. 2000 Oct 30;151(3):709-18
J:83173 Gervais FG, et al., Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat Cell Biol. 2002 Feb;4(2):95-105
J:86875 Baker SA, et al., IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. J Biol Chem. 2003 Sep 5;278(36):34211-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:119664 Houde C, et al., Hippi is essential for node cilia assembly and Sonic hedgehog signaling. Dev Biol. 2006 Dec 15;300(2):523-33
J:135560 Luby-Phelps K, et al., Spatial distribution of intraflagellar transport proteins in vertebrate photoreceptors. Vision Res. 2008 Feb;48(3):413-23
J:154656 Follit JA, et al., Characterization of mouse IFT complex B. Cell Motil Cytoskeleton. 2009 Aug;66(8):457-68
J:201466 Gdynia G, et al., BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis. Apoptosis. 2008 Mar;13(3):437-47
J:203626 Howard PW, et al., Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17. Exp Cell Res. 2013 Aug 15;319(14):2275-81
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:311093 Sorusch N, et al., SANS (USH1G) Molecularly Links the Human Usher Syndrome Protein Network to the Intraflagellar Transport Module by Direct Binding to IFT-B Proteins. Front Cell Dev Biol. 2019;7:216