Sequence Detail

ID/Version

Q8BWN8 Q9QYR8 Q8BJQ1 Q8BL20 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Peroxisomal succinyl-coenzyme A thioesterase {ECO:0000305|PubMed:16940157}; EC=3.1.2.3 {ECO:0000269|PubMed:16141203, ECO:0000269|PubMed:16940157};AltName: Full=Acyl-coenzyme A thioesterase 4; Short=Acyl-CoA thioesterase 4;Alt

Provider

SWISS-PROT

Sequence

Polypeptide 421 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acot4	acyl-CoA thioesterase 4	32	99	5	5

Sequence references in MGI

J:59046 Hunt MC, et al., Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism. J Biol Chem. 1999 Nov 26;274(48):34317-26
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103826 Westin MA, et al., The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes. J Biol Chem. 2005 Nov 18;280(46):38125-32
J:112727 Hunt MC, et al., Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs. FASEB J. 2006 Sep;20(11):1855-64
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89