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Sequence Detail
ID/Version
Q8BVM4 A2A823 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Antizyme inhibitor 2; Short=AzI2;AltName: Full=Arginine decarboxylase-like protein; Short=ADC; Short=ARGDC;AltName: Full=Ornithine decarboxylase-like protein; Short=ODC-like protein;AltName: Full=ornithine dec
Provider SWISS-PROT
Sequence
Polypeptide 459 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Azin2 antizyme inhibitor 2 83 99 2 12
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116975 Lopez-Contreras AJ, et al., Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity. J Biol Chem. 2006 Oct 13;281(41):30896-906
J:137928 Lopez-Contreras AJ, et al., Antizyme inhibitor 2 (AZIN2/ODCp) stimulates polyamine uptake in mammalian cells. J Biol Chem. 2008 Jul 25;283(30):20761-9
J:204392 Lopez-Garcia C, et al., Antizyme inhibitor 2 hypomorphic mice. New patterns of expression in pancreas and adrenal glands suggest a role in secretory processes. PLoS One. 2013;8(7):e69188
J:211327 Ramos-Molina B, et al., Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2. FEBS Open Bio. 2014;4:510-21
J:212801 Lopez-Contreras AJ, et al., Subcellular localization of antizyme inhibitor 2 in mammalian cells: Influence of intrinsic sequences and interaction with antizymes. J Cell Biochem. 2009 Jul 1;107(4):732-40
J:213902 Lopez-Contreras AJ, et al., Expression of antizyme inhibitor 2 in male haploid germinal cells suggests a role in spermiogenesis. Int J Biochem Cell Biol. 2009 May;41(5):1070-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory