Sequence Detail

ID/Version

Q8BVH9 Q9DAX6 Q9D9M6 (UniProt | EBI)

Last sequence update: 2003-10-03
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=tRNA N(3)-cytidine methyltransferase METTL6 {ECO:0000305}; EC=2.1.1.- {ECO:0000305|PubMed:28655767};AltName: Full=Methyltransferase-like protein 6 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 282 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mettl6	methyltransferase 6, methylcytidine	26	98	3	10

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:241777 Xu L, et al., Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans. J Biol Chem. 2017;292(35):14695-14703
J:299743 Ignatova VV, et al., METTL6 is a tRNA m(3)C methyltransferase that regulates pluripotency and tumor cell growth. Sci Adv. 2020 Aug;6(35):eaaz4551