Sequence Detail

ID/Version

Q8BR86 Q810H3 Q8BRS8 Q8BGQ5 Q6P555 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Kin of IRRE-like protein 3 {ECO:0000305};AltName: Full=Kin of irregular chiasm-like protein 3;AltName: Full=Nephrin-like protein 2 {ECO:0000303|PubMed:26283919};AltName: Full=mKirre {ECO:0000303|PubMed:12665856};Contains: RecName: Full=Proc

Provider

SWISS-PROT

Sequence

Polypeptide 778 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kirrel3	kirre like nephrin family adhesion molecule 3	35	107	4	9

Sequence references in MGI

J:84912 Ueno H, et al., A stromal cell-derived membrane protein that supports hematopoietic stem cells. Nat Immunol. 2003 May;4(5):457-63
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104255 Tamura S, et al., Expression of mKirre, a mammalian homolog of Drosophila kirre, in the developing and adult mouse brain. Neuroscience. 2005;133(3):615-24
J:140017 Komori T, et al., Expression of kin of irregular chiasm-like 3/mKirre in proprioceptive neurons of the dorsal root ganglia and its interaction with nephrin in muscle spindles. J Comp Neurol. 2008 Nov 1;511(1):92-108
J:171288 Nishida K, et al., Role of Neph2 in pontine nuclei formation in the developing hindbrain. Mol Cell Neurosci. 2011 Mar;46(3):662-70
J:198564 Prince JE, et al., Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression. Development. 2013 Jun;140(11):2398-408
J:228054 Martin EA, et al., The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampus. Elife. 2015;4:e09395
J:242884 Choi SY, et al., Mice lacking the synaptic adhesion molecule Neph2/Kirrel3 display moderate hyperactivity and defective novel object preference. Front Cell Neurosci. 2015;9:283