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Sequence Detail
ID/Version
Q8BQR4 Q5XJH6 Q3TJH8 Q99LE5 Q569W7 Q8CEY3 Q8C8F3 Q8C8I6 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2025-06-18
Sequence
description
from provider
RecName: Full=KAT8 regulatory NSL complex subunit 2;AltName: Full=NSL complex protein NSL2;AltName: Full=Non-specific lethal 2 homolog;
Provider SWISS-PROT
Sequence
Polypeptide 486 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Kansl2 KAT8 regulatory NSL complex subunit 2 24 102 4 46
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:282942 Karoutas A, et al., The NSL complex maintains nuclear architecture stability via lamin A/C acetylation. Nat Cell Biol. 2019 Oct;21(10):1248-1260
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:313850 Chelmicki T, et al., MOF-associated complexes ensure stem cell identity and Xist repression. Elife. 2014 May 19;3:e02024
J:339674 Tsang TH, et al., Transcriptional regulation by the NSL complex enables diversification of IFT functions in ciliated versus nonciliated cells. Sci Adv. 2023 Aug 25;9(34):eadh5598
J:347290 Guhathakurta S, et al., COX17 acetylation via MOF-KANSL complex promotes mitochondrial integrity and function. Nat Metab. 2023 Nov;5(11):1931-1952

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory