Sequence Detail

ID/Version

Q8BNJ3 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 {ECO:0000305}; Short=NMN/NaMN adenylyltransferase 2; EC=2.7.7.1 {ECO:0000250|UniProtKB:Q9BZQ4}; EC=2.7.7.18 {ECO:0000250|UniProtKB:Q9BZQ4};AltName: Full

Provider

SWISS-PROT

Sequence

Polypeptide 307 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nmnat2	nicotinamide nucleotide adenylyltransferase 2	60	100	3	214

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:192196 Hicks AN, et al., Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo. PLoS One. 2012;7(10):e47869
J:197680 Milde S, et al., Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2. PLoS Biol. 2013;11(4):e1001539
J:198686 Babetto E, et al., The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction. Cell Rep. 2013 May 30;3(5):1422-9
J:228171 Gilley J, et al., Absence of SARM1 rescues development and survival of NMNAT2-deficient axons. Cell Rep. 2015 Mar 31;10(12):1974-81
J:362033 Gilley J, et al., Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons. PLoS Biol. 2010 Jan 26;8(1):e1000300