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Sequence Detail
Q8BMF8 Q80ZC5 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2020-08-12
from provider
RecName: Full=Gliomedin;AltName: Full=Cancer-related gene liver 2 protein; Short=CRG-L2;Contains: RecName: Full=Gliomedin shedded ectodomain;Flags: Precursor;
Polypeptide 549 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Gldn gliomedin 17 72 8 4
Sequence references in MGI J:86019 Graveel CR, et al., Identification and characterization of CRG-L2, a new marker for liver tumor development. Oncogene. 2003 Mar 20;22(11):1730-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121159 Maertens B, et al., Cleavage and oligomerization of gliomedin, a transmembrane collagen required for node of ranvier formation. J Biol Chem. 2007 Apr;282(14):10647-59
J:166099 Feinberg K, et al., A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier. Neuron. 2010 Feb 25;65(4):490-502
J:203534 Kwon HS, et al., Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling. J Biol Chem. 2013 Sep 13;288(37):26357-71
J:208118 Amor V, et al., Long-Term Maintenance of Na+ Channels at Nodes of Ranvier Depends on Glial Contact Mediated by Gliomedin and NrCAM. J Neurosci. 2014 Apr 9;34(15):5089-98

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory