Sequence Detail

ID/Version

Q8BLE7 Q920B7 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Vesicular glutamate transporter 2 {ECO:0000250|UniProtKB:Q9P2U8}; Short=VGluT2 {ECO:0000303|PubMed:16942593};AltName: Full=Differentiation-associated BNPI {ECO:0000250|UniProtKB:Q9P2U8};AltName: Full=Differentiation-associated Na(+)-

Provider

SWISS-PROT

Sequence

Polypeptide 582 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	70	146	4	28

Sequence references in MGI

J:71809 Bai L, et al., Molecular and functional analysis of a novel neuronal vesicular glutamate transporter. J Biol Chem. 2001 Sep 28;276(39):36764-9
J:89958 Wojcik SM, et al., An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size. Proc Natl Acad Sci U S A. 2004 May 4;101(18):7158-63
J:91392 Schafer MK, et al., Molecular cloning and functional identification of mouse vesicular glutamate transporter 3 and its expression in subsets of novel excitatory neurons. J Biol Chem. 2002 Dec 27;277(52):50734-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:105647 Fremeau RT Jr, et al., Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites. Science. 2004 Jun 18;304(5678):1815-9
J:116159 Moechars D, et al., Vesicular glutamate transporter VGLUT2 expression levels control quantal size and neuropathic pain. J Neurosci. 2006 Nov 15;26(46):12055-66
J:279052 Nguyen MT, et al., An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye. Nat Cell Biol. 2019 Apr;21(4):420-429
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:311401 Cheret C, et al., Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels. Cell Rep. 2021 Jan 12;34(2):108623
J:324087 Preobraschenski J, et al., Vesicular glutamate transporters use flexible anion and cation binding sites for efficient accumulation of neurotransmitter. Neuron. 2014 Dec 17;84(6):1287-301