Sequence Detail

ID/Version

Q8BLA8 Q0VBN5 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Transient receptor potential cation channel subfamily A member 1 {ECO:0000312|MGI:MGI:3522699};AltName: Full=Ankyrin-like with transmembrane domains protein 1 {ECO:0000250|UniProtKB:O75762};AltName: Full=Wasabi receptor {ECO:0000303|PubMed:3

Provider

SWISS-PROT

Sequence

Polypeptide 1125 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trpa1	transient receptor potential cation channel, subfamily A, member 1	106	106	4	24

Sequence references in MGI

J:95109 Corey DP, et al., TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature. 2004 Dec 9;432(7018):723-30
J:96171 Story GM, et al., ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell. 2003 Mar 21;112(6):819-29
J:98611 Nagata K, et al., Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J Neurosci. 2005 Apr 20;25(16):4052-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:115886 Bautista DM, et al., TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell. 2006 Mar 24;124(6):1269-82
J:207026 Oh MH, et al., TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis. J Immunol. 2013 Dec 1;191(11):5371-82
J:219559 Weng HJ, et al., Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015 Feb 18;85(4):833-46
J:298782 Lin King JV, et al., A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain. Cell. 2019 Sep 5;178(6):1362-1374.e16
J:315472 Takahashi N, et al., TRPA1 underlies a sensing mechanism for O2. Nat Chem Biol. 2011 Aug 28;7(10):701-11