Sequence Detail

ID/Version

Q8BKG3 Q3V422 Q6W8S9 Q8CHK5 Q8K178 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Inactive tyrosine-protein kinase 7;AltName: Full=Protein chuzhoi;AltName: Full=Protein-tyrosine kinase 7;AltName: Full=Pseudo tyrosine kinase receptor 7;AltName: Full=Tyrosine-protein kinase-like 7;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1062 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ptk7	PTK7 protein tyrosine kinase 7	45	111	4	45

Sequence references in MGI

J:88984 Jung JW, et al., Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase. Gene. 2004 Mar 17;328:75-84
J:91298 Lu X, et al., PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature. 2004 Jul 1;430(6995):93-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:158149 Yen WW, et al., PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation. Development. 2009 Jun;136(12):2039-48
J:163834 Paudyal A, et al., The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol. 2010;10:87
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89