Sequence Detail

ID/Version

Q8BJ37 Q8VE39 (UniProt | EBI)

Last sequence update: 2003-10-24
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Tyrosyl-DNA phosphodiesterase 1; Short=Tyr-DNA phosphodiesterase 1; EC=3.1.4.- {ECO:0000250|UniProtKB:Q9NUW8};AltName: Full=Protein expressed in male leptotene and zygotene spermatocytes 501; Short=MLZ-501;

Provider

SWISS-PROT

Sequence

Polypeptide 609 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tdp1	tyrosyl-DNA phosphodiesterase 1	19	98	3	11

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:127602 Hirano R, et al., Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?. EMBO J. 2007 Nov 14;26(22):4732-43
J:127605 Katyal S, et al., TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo. EMBO J. 2007 Nov 14;26(22):4720-31
J:187568 Kogo H, et al., Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans. J Hum Genet. 2010 May;55(5):293-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89