Sequence Detail

ID/Version

Q8BHE4 Q80WR9 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transmembrane protein 108;AltName: Full=Retrolinkin {ECO:0000303|PubMed:17287360};

Provider

SWISS-PROT

Sequence

Polypeptide 574 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tmem108	transmembrane protein 108	43	98	3	11

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:119738 Liu JJ, et al., Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2223-8
J:239156 Jiao HF, et al., Transmembrane protein 108 is required for glutamatergic transmission in dentate gyrus. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1177-1182
J:239183 Xu C, et al., Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth. Mol Biol Cell. 2016 Nov 01;27(21):3342-3356
J:239200 Fu X, et al., Retrolinkin cooperates with endophilin A1 to mediate BDNF-TrkB early endocytic trafficking and signaling from early endosomes. Mol Biol Cell. 2011 Oct;22(19):3684-98