Sequence Detail

ID/Version

Q8BGU2 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cerebellin-2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 224 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cbln2	cerebellin 2 precursor protein	28	111	4	11

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112922 Miura E, et al., Distinct expression of Cbln family mRNAs in developing and adult mouse brains. Eur J Neurosci. 2006 Aug;24(3):750-60
J:117650 Bao D, et al., Cbln1 is essential for interaction-dependent secretion of Cbln3. Mol Cell Biol. 2006 Dec;26(24):9327-37
J:119795 Iijima T, et al., Characterization of a transneuronal cytokine family Cbln--regulation of secretion by heteromeric assembly. Eur J Neurosci. 2007 Feb;25(4):1049-57
J:177327 Matsuda K, et al., Cbln family proteins promote synapse formation by regulating distinct neurexin signaling pathways in various brain regions. Eur J Neurosci. 2011 Apr;33(8):1447-61
J:184952 Wei P, et al., The Cbln family of proteins interact with multiple signaling pathways. J Neurochem. 2012 Jun;121(5):717-29
J:261984 Seigneur E, et al., Genetic Ablation of All Cerebellins Reveals Synapse Organizer Functions in Multiple Regions Throughout the Brain. J Neurosci. 2018 May 16;38(20):4774-4790
J:266533 Seigneur E, et al., Cbln2 and Cbln4 are expressed in distinct medial habenula-interpeduncular projections and contribute to different behavioral outputs. Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10235-E10244
J:269669 Rong Y, et al., Glycosylation of Cblns attenuates their receptor binding. Brain Res. 2018 Sep 1;1694:129-139
J:314510 Dai J, et al., GluD1 is a signal transduction device disguised as an ionotropic receptor. Nature. 2021 Jul;595(7866):261-265