Sequence Detail

ID/Version

Q8BGD5 Q8C071 Q6NZF8 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Palmitoyl thioesterase CPT1C; EC=3.1.2.22 {ECO:0000250|UniProtKB:Q8TCG5};AltName: Full=Carnitine O-palmitoyltransferase 1, brain isoform; Short=CPTI-B;AltName: Full=Carnitine palmitoyltransferase 1C;AltName: Full=Carnitine pa

Provider

SWISS-PROT

Sequence

Polypeptide 798 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cpt1c	carnitine palmitoyltransferase 1c	48	102	3	32

Sequence references in MGI

J:79496 Price N, et al., A novel brain-expressed protein related to carnitine palmitoyltransferase I. Genomics. 2002 Oct;80(4):433-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:109455 Wolfgang MJ, et al., The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7282-7
J:186508 Carrasco P, et al., Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition. J Biol Chem. 2012 Jun 15;287(25):21224-32
J:188364 Schwenk J, et al., High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron. 2012 May 24;74(4):621-33
J:221498 Rinaldi C, et al., Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia. JAMA Neurol. 2015 May 1;72(5):561-70
J:277466 Gratacos-Batlle E, et al., Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement. Front Mol Neurosci. 2018;11:275
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:305656 Casas M, et al., Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking. J Cell Biol. 2020 Oct 5;219(10)
J:343386 Sierra AY, et al., CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity. J Biol Chem. 2008 Mar 14;283(11):6878-85