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Sequence Detail
Q80Z37 Q3USN3 Q8CGC8 Q8CFF5 Q3UPZ1 Q3UZ55 Q920L3 Q3U5B5 Q8BXP2 (UniProt | EBI) Last sequence update: 2003-06-01
Last annotation update: 2020-12-02
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RecName: Full=E3 ubiquitin-protein ligase Topors; EC=;AltName: Full=RING-type E3 ubiquitin transferase Topors {ECO:0000305};AltName: Full=SUMO1-protein E3 ligase Topors;AltName: Full=Topoisomerase I-binding RING finger protein;AltName: Ful
Polypeptide 1033 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Topors topoisomerase I binding, arginine/serine-rich 47 71 8 26
Sequence references in MGI J:98384 Lin L, et al., topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage. Oncogene. 2005 May 12;24(21):3385-96
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory