Sequence Detail

ID/Version

Q80Z25 (UniProt | EBI)

Last sequence update: 2003-06-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Centriole and centriolar satellite protein OFD1 {ECO:0000305};AltName: Full=Oral-facial-digital syndrome 1 protein homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 1017 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ofd1	OFD1, centriole and centriolar satellite protein	35	107	3	9

Sequence references in MGI

J:83802 Ferrante MI, et al., Characterization of the OFD1/Ofd1 genes on the human and mouse sex chromosomes and exclusion of Ofd1 for the Xpl mouse mutant. Genomics. 2003 Jun;81(6):560-9
J:106035 Ferrante MI, et al., Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification. Nat Genet. 2006 Jan;38(1):112-7
J:132369 Corbit KC, et al., Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat Cell Biol. 2008 Jan;10(1):70-6
J:161171 Singla V, et al., Ofd1, a human disease gene, regulates the length and distal structure of centrioles. Dev Cell. 2010 Mar 16;18(3):410-24
J:203424 Tang Z, et al., Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites. Nature. 2013 Oct 10;502(7470):254-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89