Sequence Detail

ID/Version

Q80X90 Q8VHX4 Q8VHX7 E9QNV9 Q99KY3 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Filamin-B; Short=FLN-B;AltName: Full=ABP-280-like protein;AltName: Full=Actin-binding-like protein;AltName: Full=Beta-filamin;

Provider

SWISS-PROT

Sequence

Polypeptide 2602 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Flnb	filamin, beta	31	113	3	102

Sequence references in MGI

J:79977 Sheen VL, et al., Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact. Hum Mol Genet. 2002 Nov 1;11(23):2845-54
J:80557 van der Flier A, et al., Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits. J Cell Biol. 2002 Jan 21;156(2):361-76
J:174390 Gay O, et al., RefilinB (FAM101B) targets FilaminA to organize perinuclear actin networks and regulates nuclear shape. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11464-9
J:201396 Sakane A, et al., Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins. Genes Cells. 2013 Sep;18(9):810-22
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:210363 Mizuhashi K, et al., Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements. Hum Mol Genet. 2014 Jun 1;23(11):2953-67
J:251576 Thottakara T, et al., The E3 ubiquitin ligase Asb2beta is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation. J Mol Cell Cardiol. 2015 Oct;87:214-24
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89