Sequence Detail

ID/Version

Q80TS3 Q3UM79 Q80T56 Q5HZJ6 Q504Z9 Q3UHI7 (UniProt | EBI)

Last sequence update: 2007-01-09
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Adhesion G protein-coupled receptor L3 {ECO:0000312|MGI:MGI:2441950};AltName: Full=Latrophilin-3 {ECO:0000312|MGI:MGI:2441950};AltName: Full=Lectomedin-3 {ECO:0000312|MGI:MGI:2441950};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1537 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adgrl3	adhesion G protein-coupled receptor L3	58	97	3	18

Sequence references in MGI

J:83410 Vassilatis DK, et al., The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4903-8
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:185872 Wallis D, et al., Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction. Brain Res. 2012 Jun 29;1463:85-92
J:211177 O'Sullivan ML, et al., LPHN3, a presynaptic adhesion-GPCR implicated in ADHD, regulates the strength of neocortical layer 2/3 synaptic input to layer 5. Neural Dev. 2014;9:7
J:224713 Jackson VA, et al., Structural basis of latrophilin-FLRT interaction. Structure. 2015 Apr 7;23(4):774-81
J:224730 O'Sullivan ML, et al., FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development. Neuron. 2012 Mar 8;73(5):903-10
J:225579 Ranaivoson FM, et al., Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development. Structure. 2015 Sep 1;23(9):1665-77
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89