Sequence Detail

ID/Version

Q80TR1 Q7TNE5 Q3UH90 Q80T49 (UniProt | EBI)

Last sequence update: 2007-01-09
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Adhesion G protein-coupled receptor L1 {ECO:0000312|MGI:MGI:1929461};AltName: Full=Calcium-independent alpha-latrotoxin receptor 1 {ECO:0000250|UniProtKB:O88917}; Short=CIRL-1 {ECO:0000250|UniProtKB:O88917};AltName: Full=Latrophilin-

Provider

SWISS-PROT

Sequence

Polypeptide 1466 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adgrl1	adhesion G protein-coupled receptor L1	50	108	3	19

Sequence references in MGI

J:83410 Vassilatis DK, et al., The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4903-8
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:224730 O'Sullivan ML, et al., FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development. Neuron. 2012 Mar 8;73(5):903-10
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:341520 Vitobello A, et al., ADGRL1 haploinsufficiency causes a variable spectrum of neurodevelopmental disorders in humans and alters synaptic activity and behavior in a mouse model. Am J Hum Genet. 2022 Aug 4;109(8):1436-1457