Sequence Detail

ID/Version

Q80TN5 Q8BYQ2 Q8BJ08 Q8BYQ6 (UniProt | EBI)

Last sequence update: 2004-04-13
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Palmitoyltransferase ZDHHC17 {ECO:0000305}; EC=2.3.1.225 {ECO:0000269|PubMed:15489887, ECO:0000269|PubMed:15603741, ECO:0000269|PubMed:25253725};AltName: Full=Acyltransferase ZDHHC17 {ECO:0000305|PubMed:28167757}; EC=2.3.1.-

Provider

SWISS-PROT

Sequence

Polypeptide 632 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zdhhc17	zinc finger, DHHC domain containing 17	65	99	3	13

Sequence references in MGI

J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:94875 Fukata M, et al., Identification of PSD-95 Palmitoylating Enzymes. Neuron. 2004 Dec 16;44(6):987-96
J:94960 Ducker CE, et al., Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase. Oncogene. 2004 Dec 9;23(57):9230-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143386 Goytain A, et al., Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport. J Biol Chem. 2008 Nov 28;283(48):33365-74
J:221517 Lemonidis K, et al., The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity. Mol Biol Cell. 2014 Dec 1;25(24):3870-83
J:231844 Shi W, et al., ZDHHC17 promotes axon outgrowth by regulating TrkA-tubulin complex formation. Mol Cell Neurosci. 2015 Sep;68:194-202
J:233660 Lemonidis K, et al., Identification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13 S-Acyltransferases. J Biol Chem. 2015 Sep 4;290(36):21939-50
J:248366 Lemonidis K, et al., Peptide array-based screening reveals a large number of proteins interacting with the ankyrin-repeat domain of the zDHHC17 S-acyltransferase. J Biol Chem. 2017 Oct 20;292(42):17190-17202
J:258534 Skotte NH, et al., Palmitoylation of caspase-6 by HIP14 regulates its activation. Cell Death Differ. 2017 Mar;24(3):433-444
J:284989 Greaves J, et al., Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein. J Biol Chem. 2008 Sep 5;283(36):25014-26
J:287027 Greaves J, et al., Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1365-E1374