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Sequence Detail
ID/Version
Q7TT37 Q8CBI3 Q3UHY6 Q8C6B3 Q7TQH1 Q8VHU5 Q9CT81 Q8CH82 Q8VHV9 (UniProt | EBI) Last sequence update: 2004-03-01
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=Elongator complex protein 1; Short=ELP1;AltName: Full=IkappaB kinase complex-associated protein; Short=IKK complex-associated protein;
Provider SWISS-PROT
Sequence
Polypeptide 1333 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Elp1 elongator complex protein 1 15 108 3 17
Sequence references in MGI J:72647 Cuajungco MP, et al., Cloning, characterization, and genomic structure of the mouse Ikbkap gene. DNA Cell Biol. 2001 Sep;20(9):579-86
J:73344 Coli R, et al., Genomic organization and chromosomal localization of the mouse IKBKAP gene. Gene. 2001 Nov 14;279(1):81-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:150477 Creppe C, et al., Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin. Cell. 2009 Feb 6;136(3):551-64
J:187591 Close P, et al., DERP6 (ELP5) and C3ORF75 (ELP6) Regulate Tumorigenicity and Migration of Melanoma Cells as Subunits of Elongator. J Biol Chem. 2012 Sep 21;287(39):32535-45
J:200015 Lin FJ, et al., Ikbkap/Elp1 deficiency causes male infertility by disrupting meiotic progression. PLoS Genet. 2013 May;9(5):e1003516
J:287112 Yang KT, et al., Loss of Ikbkap/Elp1 in mouse oocytes causes spindle disorganization, developmental defects in preimplantation embryos and impaired female fertility. Sci Rep. 2019 Dec 11;9(1):18875
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory