Sequence Detail

ID/Version

Q7TSP5 Q8K091 Q7TPH5 (UniProt | EBI)

Last sequence update: 2003-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=V-set domain containing T-cell activation inhibitor 1;AltName: Full=B7 homolog 4; Short=B7-H4;AltName: Full=Immune costimulatory protein B7-H4;AltName: Full=Protein B7S1;AltName: Full=T cell costimulatory molecule B7x;Flags: Precurso

Provider

SWISS-PROT

Sequence

Polypeptide 283 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Vtcn1	V-set domain containing T cell activation inhibitor 1	27	97	3	20

Sequence references in MGI

J:85122 Prasad DV, et al., B7S1, a novel B7 family member that negatively regulates T cell activation. Immunity. 2003 Jun;18(6):863-73
J:85242 Sica GL, et al., B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. Immunity. 2003 Jun;18(6):849-61
J:94876 Zang X, et al., B7x: a widely expressed B7 family member that inhibits T cell activation. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10388-92
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112130 Suh WK, et al., Generation and characterization of B7-H4/B7S1/B7x-deficient mice. Mol Cell Biol. 2006 Sep;26(17):6403-11