Sequence Detail

ID/Version

Q7TQJ8 Q8CG89 (UniProt | EBI)

Last sequence update: 2003-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Wilms tumor protein 1-interacting protein; Short=WT1-interacting protein;

Provider

SWISS-PROT

Sequence

Polypeptide 398 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wtip	WT1 interacting protein	46	99	3	7

Sequence references in MGI

J:90773 Srichai MB, et al., A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus. J Biol Chem. 2004 Apr 2;279(14):14398-408
J:131451 Ayyanathan K, et al., The Ajuba LIM domain protein is a corepressor for SNAG domain mediated repression and participates in nucleocytoplasmic Shuttling. Cancer Res. 2007 Oct 1;67(19):9097-106
J:155130 van Wijk NV, et al., The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling. Biochem Biophys Res Commun. 2009 Dec 11;390(2):211-6
J:161733 Kim JH, et al., Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport. J Biol Chem. 2010 Mar 26;285(13):9995-10004
J:180032 Kim JH, et al., WT1-interacting protein (Wtip) regulates podocyte phenotype by cell-cell and cell-matrix contact reorganization. Am J Physiol Renal Physiol. 2012 Jan;302(1):F103-15
J:183217 Langer EM, et al., Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus. Dev Cell. 2008 Mar;14(3):424-36