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Sequence Detail
Q7TNJ0 Q6R315 B2RT61 Q9D619 Q7TNI9 (UniProt | EBI) Last sequence update: 2003-10-01
Last annotation update: 2019-12-11
from provider
RecName: Full=Dendritic cell-specific transmembrane protein; Short=DC-STAMP; Short=mDC-STAMP;AltName: Full=Dendrocyte-expressed seven transmembrane protein;AltName: Full=Transmembrane 7 superfamily member 4;
Polypeptide 470 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Dcstamp dendrocyte expressed seven transmembrane protein 30 0 9 4
Sequence references in MGI J:93945 Kukita T, et al., RANKL-induced DC-STAMP is essential for osteoclastogenesis. J Exp Med. 2004 Oct 4;200(7):941-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100555 Yagi M, et al., DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J Exp Med. 2005 Aug 1;202(3):345-51
J:140227 Sawatani Y, et al., The role of DC-STAMP in maintenance of immune tolerance through regulation of dendritic cell function. Int Immunol. 2008 Oct;20(10):1259-68
J:183967 Eleveld-Trancikova D, et al., The DC-derived protein DC-STAMP influences differentiation of myeloid cells. Leukemia. 2008 Feb;22(2):455-9
J:184052 Eleveld-Trancikova D, et al., The dendritic cell-derived protein DC-STAMP is highly conserved and localizes to the endoplasmic reticulum. J Leukoc Biol. 2005 Mar;77(3):337-43
J:184740 Miyamoto T, The dendritic cell-specific transmembrane protein DC-STAMP is essential for osteoclast fusion and osteoclast bone-resorbing activity. Mod Rheumatol. 2006;16(6):341-2
J:184741 Yagi M, et al., Role of DC-STAMP in cellular fusion of osteoclasts and macrophage giant cells. J Bone Miner Metab. 2006;24(5):355-8
J:244641 Miyamoto H, et al., Osteoclast stimulatory transmembrane protein and dendritic cell-specific transmembrane protein cooperatively modulate cell-cell fusion to form osteoclasts and foreign body giant cells. J Bone Miner Res. 2012 Jun;27(6):1289-97

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory