Sequence Detail

ID/Version

Q7TMY7 Q8R3V7 B2KGD8 Q811I3 Q8C8A9 Q8R2P6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Importin-8 {ECO:0000312|MGI:MGI:2444611}; Short=Imp8;AltName: Full=Ran-binding protein 8; Short=RanBP8 {ECO:0000312|MGI:MGI:2444611};

Provider

SWISS-PROT

Sequence

Polypeptide 1010 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ipo8	importin 8	15	103	3	6

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:308340 Van Gucht I, et al., A human importin-beta-related disorder: Syndromic thoracic aortic aneurysm caused by bi-allelic loss-of-function variants in IPO8. Am J Hum Genet. 2021 Jun 3;108(6):1115-1125
J:338158 Zhang Y, et al., IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and Translocation. Stem Cells. 2022 Nov 29;40(11):1020-1030