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Sequence Detail
Q7TMA4 (UniProt | EBI) Last sequence update: 2003-10-01
Last annotation update: 2019-05-08
from provider
RecName: Full=Free fatty acid receptor 4;AltName: Full=G-protein coupled receptor 120;AltName: Full=G-protein coupled receptor GT01;AltName: Full=Omega-3 fatty acid receptor 1;
Polypeptide 361 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Ffar4 free fatty acid receptor 4 27 0 8 15
Sequence references in MGI J:95456 Hirasawa A, et al., Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med. 2005 Jan;11(1):90-94
J:99416 Katsuma S, et al., Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1. J Biol Chem. 2005 May 20;280(20):19507-15
J:146309 Matsumura S, et al., Colocalization of GPR120 with phospholipase-Cbeta2 and alpha-gustducin in the taste bud cells in mice. Neurosci Lett. 2009 Jan 30;450(2):186-90
J:161517 Cartoni C, et al., Taste preference for fatty acids is mediated by GPR40 and GPR120. J Neurosci. 2010 Jun 23;30(25):8376-82
J:166091 Oh da Y, et al., GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell. 2010 Sep 3;142(5):687-98
J:182599 Ichimura A, et al., Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature. 2012 Mar 15;483(7389):350-4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory